The Smartest Doctor in the Room

Dizziness is one of the most common symptoms patients experience, yet it is also one of the most misunderstood. In this episode of The Smartest Doctor In The Room, Dr. Dean Mitchell is joined by neurologist and dizziness specialist Dr. Amir Kheradmand to explain what dizziness really means, why it is so difficult to diagnose, and when it may signal a more serious condition.

The conversation breaks down the key differences between dizziness, vertigo, and lightheadedness, why medications like meclizine are often outdated, and how careful history taking and eye movement exams can help determine whether symptoms...

Join Dr. Dean Mitchell on The Smartest Doctor In The Room as he reflects on more than 25 years in medical practice and explores how medicine has evolved and what should never be lost along the way. From handwritten charts and prescription pads to electronic records, telehealth, and AI driven information, Dr. Mitchell shares firsthand insights into how technology has transformed the doctor patient relationship for better and for worse.

In this thoughtful conversation, he discusses the importance of eye contact, physical exams, careful history taking, and genuine human connection in an era of screens, shortcuts, and online...

In this episode of The Smartest Doctor In The Room, host Dr. Dean Mitchell sits down with world-renowned allergist and immunologist Dr. Thomas Platts-Mills to explore the shocking true story behind a healthy airline pilot who died after what seemed like a simple steak dinner. The cause was not choking or food poisoning. It was a delayed, deadly allergic reaction from a condition many people and even many doctors still overlook.

Dr. Mitchell and Dr. Platts-Mills walk listeners through the mystery of alpha gal syndrome, also known as red meat allergy syndrome, a unique allergy triggered by...

In this episode of The Smartest Doctor In The Room, Dr. Dean Mitchell sits down with neurologist and author Dr. Ray Dorsey to explore why Parkinson’s disease has become the world’s fastest growing brain disorder. Dr. Dorsey explains what Parkinson’s looks like, the early signs many people miss, and why it is not simply a disease of aging or genetics.

They dive into the mounting evidence that environmental exposures are driving the rise in cases. Dr. Dorsey breaks down the roles of air pollution, pesticides, dry cleaning chemicals, contaminated drinking water, and repeated head trauma...

Explore how EMDR therapy can help heal deep psychological trauma with psychiatric nurse practitioner and EMDR expert Susan Sullivan. In this episode of The Smartest Doctor In The Room, host Dr Dean Mitchell talks with Susan about her unique path from trauma intensive care nursing to advanced work in psychiatry and psychotherapy.

Susan explains what EMDR really is, how adaptive information processing works in the brain, and why EMDR can be so powerful for people who feel stuck after years of traditional talk therapy. She shares how EMDR intensives differ from weekly sessions, and why careful preparation...

Celebrate our 200th episode as Dr. Dana Cohen turns the tables and interviews host Dr. Dean Mitchell about his new book on Candida and what it really takes to heal. They trace the evolution from Dr. William Crook’s classic work to today’s microbiome science, explain why Candida overgrowth is still misunderstood, and lay out a clear clinical approach that actually helps patients feel better fast.

Listen for practical guidance on recognizing symptoms beyond vaginal yeast infections, the link between Candida and issues like chronic sinusitis, brain fog, and fatigue, and why diversity in the microbiome matt...

When you or someone you love lands in the ER, every choice matters. Dr. Dean Mitchell sits down with Dr. Tony Dajer, a recently retired emergency physician with four decades on the front lines, to share clear, practical steps that help you get the care you need when minutes count.

They cover how to prepare before you go, what to say at triage, and why bringing your medications and a concise medical history can speed decision making. You will hear when calling an ambulance is the smartest move, how to choose between urgent care and the ER...

In this episode of The Smartest Doctor in the Room, Dr. Dean Mitchell sits down with headache specialist Dr. Robert Kaniecki from the University of Pittsburgh Medical School to break down everything you need to know about chronic headaches and migraines. Together they explore the different types of headaches, how to properly evaluate and diagnose them, and the latest treatments - from classic medications to cutting-edge options like CGRP inhibitors and Botox therapy. They also discuss common triggers such as stress, sleep, diet, and screen time, and when imaging tests like MRIs are actually necessary. Whether you experience tension...

Can food allergies be treated safely without lifelong maintenance doses? In this episode of The Smartest Doctor in the Room, Dr. Dean Mitchell sits down with Dr. Moshe Ben Shoshan, Associate Professor at McGill University Health Centre, to explore the latest breakthroughs in food allergy treatment. Together they discuss low dose oral immunotherapy, the science behind desensitization, and how early exposure to allergenic foods like peanuts may actually reduce allergy risk. They also unpack real world challenges with treatment adherence, why milk allergies can be more dangerous than peanuts, and what new research is revealing about prevention, immunotherapy, and...

In this wide ranging conversation, Dr. Dean Mitchell sits down with Professor Edward Quadros of SUNY Downstate to explore the critical roles of folate vitamin B9 and vitamin B12 in brain development and lifelong health. We unpack why some children show low cerebrospinal fluid folate despite a normal diet, how autoantibodies to the folate receptor can block folate from reaching the brain, and what the folate receptor antibody test FRAT reveals. Professor Quadros explains the research behind folinic acid leucovorin as a folate enhancer, what clinical studies show in children on the spectrum, and why earlier treatment tends to...

In this powerful episode, we explore one of the most important—and least understood—medical challenges of our time: how brain injury and aging impact mental health, behavior, and society. Our host is joined by renowned neuropathologist Dr. John Crary, a leading expert on brain diseases at Mount Sinai, to unpack the science and lived reality behind concussions, CTE (chronic traumatic encephalopathy), dementia, and more.

Dr. Crary shares his early fascination with neuroanatomy, how pathology reveals the hidden stories inside every brain, and why repetitive mild head trauma—not just big hits—may be the true danger in conta...

What should you do when water damage strikes—whether it’s a burst pipe, a flooded basement, or a slow leak you didn’t notice until it was too late? In this episode, Dr. Mitchell sits down with trusted mold inspector Joseph Reiss to unpack the essentials of mold prevention, testing, and remediation. They cover what to do in the first 24 hours after water damage, why carpets are mold magnets, how to safely contain and remove contaminated materials, and which testing methods actually help identify hidden mold.

Joseph also shares insights on flood-proof home design, how to avoid...

Adverse drug reactions and allergic responses to medications and vaccines are no longer rare side effects—they’re a growing medical challenge. In this episode, we sit down with Dr. Mariana Castells, Professor of Medicine at Harvard Medical School, Director of the Mastocytosis Center of Excellence, and Director of the Drug Hypersensitivity and Desensitization Center at Brigham and Women’s Hospital.

We explore:

What’s it really like to be a medical student in 2025? Host Dr. Mitchell sits down with second-year students Nya Evans and Marco Halabi from Touro College of Osteopathic Medicine for a candid conversation about why they chose medicine, the challenges of medical school today, and how training has evolved since the 1980s. From simulation labs and self-directed learning to the psychological toll of training and the role of AI in the future of medicine, this episode offers a rare first-hand look at how tomorrow’s physicians are being shaped. Both insightful and personal, it’s a reminder that while...

Brain fog—a term once absent from the medical lexicon—has become one of the most debilitating and puzzling symptoms of Long COVID. But what exactly is happening inside the body to cause this cognitive impairment? Is it just inflammation, or is there a more complex mechanism at play?

In this episode, we sit down with leading immunologist Dr. Terry Harville, Medical Director of the Special Immunology Laboratory at the University of Arkansas for Medical Sciences. Dr. Harville takes us on a deep dive into the unique relationship between the SARS-CoV-2 virus and the human immune system, expl...

What if your child’s sudden anxiety, OCD, or tics weren’t behavioral—but biological? In this eye-opening episode, we welcome back Dr. Jill Crista, a leading expert in naturopathic medicine and mold-related illness, to explore a lesser-known but critically important condition: PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections) and its broader counterpart, PANS (Pediatric Acute-onset Neuropsychiatric Syndrome).

What if a simple strep throat infection could lead to sudden-onset OCD, anxiety, tics, or even psychosis in children? Dr. Crista breaks down the groundbreaking science behind how infections—and even environmental toxins like mold and glyphosate—can trigge...

Ever looked in the mirror and wondered, What if I tweaked this? You’re not alone. Plastic surgery—once reserved for the rich and famous—is now a reality for everyday people seeking confidence and self-improvement. But how do you know if it’s right for you? And what separates a natural-looking result from a "wind tunnel face"?

On this episode, host Dean Mitchell sits down with Dr. Robert Freund, a top Manhattan plastic surgeon, inventor of the Teardrop Breast Lift, and author of Cosmetic Breast Surgery and A More Beautiful You. From their shared high school days to...

In this episode of The Smartest Doctor in the room, we welcome back Dr. Kevin Tracey, a pioneering neurosurgeon, scientist, and leading expert in bioelectric medicine—specifically, the healing power of the vagus nerve. Dr. Tracey’s work has proven that electrical stimulation of the vagus nerve can reverse autoimmune conditions without medication, a discovery that could dramatically transform modern medicine.

Dr. Tracey also shares insights from his new book, The Great Nerve, which explores the vagus nerve’s role in health, longevity, and holistic healing. Plus, we discuss why he’s a top candidate for a Nobel Pr...

In this episode of The Smartest Doctor in the Room, Dr. Mitchell sits down with renowned nutritionist, chef, and author Mia Rigden to explore her holistic approach to healthy eating for individuals and families. Mia shares her expert insights on balancing nutrition science with the emotional and practical aspects of food, offering actionable tips for sustainable wellness.

Mia also opens up about her work with high-profile clients, her bestselling books FoodWise and The Well Journal, and her mission to make nutritious home cooking accessible through her Substack, Between Meals. Whether you're a busy parent, a fitness enthusiast...

What separates elite athletes from the rest? While we often focus on strength, speed, and skill, one critical factor is frequently overlooked: vision. In this eye-opening episode, we sit down with Dr. Daniel Laby, a leading sports vision ophthalmologist who has worked with the Los Angeles Dodgers, NBA teams, Formula 1 drivers, and Olympic athletes.

Whether you’re a pro athlete, a weekend competitor, or just someone who wants to protect and optimize your eyesight, this episode will change how you see the game—literally. Dr. Laby also shares insights from his book, "Eye of the Champion: Unlocking the...

In this episode of The Smartest Doctor in the Room, host Dr. Dean Mitchell sits down with Dr. Bruce Farber, Chief of Public Health and Epidemiology at Northwell Health, to dissect the infectious disease threats making headlines—from resurgent measles outbreaks to the looming specter of avian flu. With decades of experience battling HIV, COVID-19, and hospital-acquired infections, Dr. Farber offers a frontline perspective on:

In this episode of the Smartest Doctor in the Room, host Dr. Dean Mitchell sits down with renowned immunologist and autism researcher Dr. Judy Van der Water from the UC Davis MIND Institute. Together, they dive deep into the groundbreaking research linking maternal immune health, the fetal microbiome, and the rising prevalence of autism spectrum disorders (ASD).

Dr. Van der Water shares her pioneering work on gestational immune dysregulation, including the role of maternal autoantibodies (MAR antibodies) in fetal brain development—and why these findings challenge long-held misconceptions about autism’s origins. They also tackle tough questions: Is a...

In this episode of The Smartest Doctor in the Room, we explore the complex world of gastrointestinal health with leading expert Dr. Rao. The doctors discuss the wide ranging impacts of poor gut health, from digestive issues, to brain fog. They share groundbreaking insights into diagnosis, the role of fungi like Candida, the effects of medications like proton pump inhibitors, and innovative treatment approaches.

Dr. Rao and Dr. Mitchell also share their frustrations with the slow speed at which new and proven techniques become widely adopted, and the inflexible attitude towards new discoveries that is all too...

In this episode of The Smartest Doctor in the Room, we delve into the true essence of effective weight training and holistic wellness with author and four-time world weightlifting champion, Jerzy Gregorek. With a background rooted in resilience, philosophy, and a passion for helping others, Jerzy shares his expert insights on how proper strength training can transform not only your body but also elevate your spirit.
 
Discover practical tips on injury prevention, the importance of flexibility, recovery techniques, and how to cultivate a lifestyle that promotes longevity and mental clarity. Whether you're an athlete, a busy professional, o...

In this episode of The Smartest Doctor in the Room, Dr. Mitchell welcomes allergy expert Dr. David Golden Associate Professor at Johns Hopkins to explore the critical topic of anaphylaxis — the most dangerous allergy. They discuss what anaphylaxis really is, how it presents differently in individuals, and the latest advancements in treatment, including the groundbreaking FDA-approved nasal spray as an alternative to injectable epinephrine.

Plus, hear insights on allergy testing, immunotherapy options like Xolair, and the evolving protocols in emergency management. Whether you're an allergy sufferer, caregiver, or healthcare professional, this episode provides vital information to help yo...

In this episode, we dive into the often-misunderstood world of chronic sinusitis, exploring why antibiotics aren't always the answer and uncovering effective, natural, and integrative treatment strategies. Join us as Dr. Linda Dahl, a seasoned ENT specialist with a unique background—from ringside boxing to Broadway—shares her holistic approach to sinus health, the importance of microbiome balance, and when surgery is truly necessary. 

We also discuss the critical role of allergies, the pitfalls of overprescribing medications, the significance of personalized care, and how holistic practices can help with maternal health. Whether you're a patie...

In this inspiring episode of the "Smartest Doctor in the Room" Dr. Dean Mitchell, celebrates Food Allergy Awareness Month by speaking with a remarkable young advocate, 12-year-old Zacky Muñoz. Along with his mother Priscilla, Zacky shares his personal journey living with food allergies, the challenges he faces, and his passionate fight to improve safety and awareness through the Zacky Fast Act legislation in California. Plus, discover the latest advances in allergy treatments, innovative devices like needle-free epinephrine, and how social media is empowering youth to become advocates. Join us for a heartfelt conversation about resilience, advocacy, and hope f...

In this insightful episode, Dr. Mitchell welcomes back renowned mold inspector Joe Reiss to discuss crucial strategies for identifying, addressing, and preventing water damage and mold in your home. From handling water leaks and basement puddles to understanding the complexities of mold species and their health impacts, Joe shares expert tips on source control, environmental assessment, and choosing reputable remediation professionals.

Plus, learn how your to care for your home and why indoor air quality is vital for its health, as well as your own. Whether you're a homeowner, renter, or concerned about mold exposure, this episode...

Welcome back to The Smartest Doctor in the Room with Dr. Dean Mictchell. Today on this enlightening episode, he explores the fascinating world of archaeological nutrition with Culinary Archaeologist Lisa Roberts. Discover how ancient food practices, cultural rituals, and traditional diets from the Mediterranean and beyond can offer powerful insights into holistic health, autoimmune conditions, and stress management today.

Lisa shares her personal journey from health challenges to becoming a pioneer in blending archaeology, culinary arts, and nutrition — revealing practical tips on nourishing the body, mind, and spirit. Whether you're interested in the science behind the Mediterranean di...

This week on the Smartest Doctor in the Room, join host Dr. Dean Mitchell as he welcomes Dr. Ryan Vandrey, a leading expert from Johns Hopkins, to navigate the complex and evolving world of cannabis, colloquially known as marijuana.

In this episode, Dr. Mitchell and Dr. Vandrey delve into the science behind cannabis, explaining the differences between THC, CBD, and hemp-derived products. They'll discuss the historical shift of cannabis from a stigmatized substance, to its place in the medical field, touching on potential medicinal benefits, the challenges of research, and the critical importance of consulting with your...

Welcome back to The Smartest Doctor in the Room! This week Dr. Mitchell dives into the fascinating world of eye health with the brilliant Dr. Rudrani Banik, a board-certified ophthalmologist, expert in functional holistic medicine, and the author of “Beyond Carrots”.

As the architect behind the upcoming Eye Health Summit, Dr. Banik is here to shed light on how we can proactively safeguard our precious vision. During the conversation, we explore the complex relationship between nutrition and eye health, debunk myths about popular beliefs (like whether eating carrots truly gives you 20/20 vision), and discuss how factors such as o...

In this episode of The Smartest Doctor in the Room, Dr. Dean Mitchell dives deep into an unexpected intersection of sports and health: the impact of spring allergies on golfers and fans alike, notably during the prestigious Masters Tournament in Augusta, Georgia—ranked as one of the worst allergy hotspots in the country.

He explores why renowned athletes like Rory McIlroy and Tiger Woods grapple with allergies on the course, recounting their struggles and solutions. Learn about innovative treatments like sublingual allergy drops that can potentially reverse allergies and offer hope to sufferers. Dr. Mitchell emphasizes the im...

In this riveting episode of "The Smartest Doctor in the Room," Dr. Dean Mitchell dives deep into the often-overlooked amino acid, homocysteine—a key player in heart health that could be more important than cholesterol in assessing your risk for heart disease.

Join Dr. Mitchell as he takes you on a journey through the evolution of heart disease research, spotlighting the groundbreaking work of Dr. Kilmer McCully, the man who dared to challenge the status quo on cholesterol and spark a medical revolution about inflammation’s role in cardiovascular health.

Dr. Mitchell also shares personal anec...

Join us for a special "Smartest Doctor in the Room" minisode, as your host, Dr. Dean Mitchell, talks on how this podcast was born!

We highlight the motivation behind seeking out groundbreaking treatments in holistic medicine, the “aha” moment that brought the show to life, and Dr. Mitchell’s gratitude for the remarkable guests who have shared their expertise over the years. Throughout the conversation, Dr. Mitchell emphasizes the lasting impact of podcasting as a resource for ongoing education and health empowerment for doctors and health-conscious individuals alike!

Tune in for insights, thoughtful stories, and a...

Welcome back to another episode of the Smartest Doctor in the Room. Today, Dr. Mitchell delves into a topic that has become increasingly relevant in our everyday lives—how to fight a virus naturally.

In this episode, Dr. Mitchell shares a recent personal experience with parainfluenza, a lesser-known virus but one with severe side-effects. After successfully getting the sickness diagnosed, Dr. Mitchell began implementing a 3 part plan that helped aid his recovery and got him back on his feet. Tune in to hear the details!

This episode aims to empower you and your loved ones so...

In this episode of "The Smartest Doctor in the Room," host Dr. Mitchell engages in a deep-dive discussion with renowned immunologist Dr. Terry Harville. Together, they unravel the complexities of the immune system, exploring its pivotal role in chronic illnesses like Long COVID, Myalgic Encephalitis, and Chronic Lyme disease. Dr. Harville and Dr. Mitchell emphasize the importance of “Thinking Like an Immunologist” and how that should affect our approach to treating patients in the long haul.

Join us as we explore cutting-edge concepts and practical advice for enhancing immune health, shedding light on the intricate dance between infe...

In this enlightening episode of The Smartest Doctor in the Room, we dive deep into the overlooked complexities of meditation, exploring both its transformative benefits and the potential adverse effects that can arise. Join Dr. Dean Mitchell as he welcomes Dr. Willoughby Britton, a pioneering expert from Brown University, whose extensive research reveals that meditation isn't the panacea it's often thought to be.

Whether you're a seasoned meditator, a curious beginner, or a mental health professional, this episode will challenge you to take a closer look at your own motivations, and those of wellness professionals so that...

In this episode of The Smartest Doctor in the Room, we dive into the captivating world of cutting edge eye care with Dr. Andrew Lam, a talented ophthalmologist and Assistant Professor at the University of Massachusetts Medical School. We discuss his book, "Saving Sight," which reflects on the history and advancements in the field, shares personal anecdotes from his compelling career, and provides digestible metaphors to help readers understand the inner workings of our windows to the soul.

Join us as we explore the critical importance of vision, the emotional challenges of blindness, and the innovative treatments...

In this episode of The Smartest Doctor in the Room, Dr. Dean Mitchell is joined by renowned rheumatologist Dr. John Stone, the Director of the Clinical Rheumatology Section at Massachusetts General Hospital. With a wealth of knowledge in autoimmune diseases, Dr. Stone shares groundbreaking insights on conditions that are often misunderstood and misdiagnosed.

Dr. Stone explores the complexities of autoimmune diseases, from the most common theories of how autoimmune diseases function, to the challenges in early diagnosis. Dr. Stone also makes a point to cover the latest advances in the field, including how new biologic therapies are...

In this episode, Dr. Dean Mitchell welcomes back Dr. Paul Offit, the Maurice Hilleman Professor of Vaccinology at the University of Pennsylvania's Perelman School of Medicine, to discuss the current state of vaccine misinformation and the importance of understanding how vaccines work. 

In the episode, listeners will take a journey through the history of vaccines, the great minds whose scientific discoveries shaped the fabric of our society, and Dr. Mitchell and Dr. Dean's own experience with vaccines in their respective careers. The conversation then turns to cutting edge dialogue, with Dr. Offit expressing his own concerns with v...

In this episode of The Smartest Doctor in the Room, join Dr. Dean Mitchell as he dives into the critical yet often underestimated world of teenage sleep. Our guest, Professor Mary Carskadon, (a leading researcher in adolescent sleep health at Brown University) sheds light on the significant impacts of sleep deprivation in teenagers. This simple, yet critical component of our daily routines can lead to increased risks of depression, addiction, and even driving accidents, particularly in our youth. 

Professor Carskadon explains the biological changes occurring in the teenage brain and how these affect their sleep patterns and d...

In this timely episode of The Smartest Doctor in the Room, Dr. Dean Mitchell interviews Dr. Catharina Giudice, an emergency room physician and fellow at the Center for Climate, Health, and Global Environment at Harvard's T.H. Chan School of Public Health. As wildfires ravage cities like Los Angeles and floods sweep through the Southeastern U.S., these 2 doctors (and concerned citizens) bring awareness to the wide-reaching impacts of climate change.

Dr. Giudice shares her insights on the alarming connection between climate-related disasters and our well-being. From the respiratory dangers posed by fine particulate matter (PM2.5 and...

In light of the recent challenges faced by Los Angeles, we begin with a heartfelt acknowledgment of the efforts and resilience of its residents and a thanks to Dr. Pimentel for taking the time to join us despite it all.

In the first episode of the New Year, host Dr. Dean Mitchell welcomes back the esteemed Dr. Mark Pimentel, a leading gastroenterologist from UCLA, to explore the critical role of the gut microbiome in overall health. As we dive into this fascinating discussion, we’ll uncover why taking care of your gut is essential—not just for...

In this enlightening episode of the Smarter Dr. in the Room podcast, host Dr. Dean Mitchell sits down with thoracic surgeon Dr. Matthew Inra from the Donald and Barbara Zucker School of Medicine at Northwell Hospital. Together, they unravel the often misunderstood symptom of shortness of breath—a common experience that can signal a variety of underlying issues beyond just lung problems.

Shortness of breath is a common symptom, but its causes can be unexpected. Join Dr. Dean Mitchell as he talks with Dr. Matthew Inra, a renowned thoracic surgeon, about uncovering hidden reasons behind breathing di...

Ehlers-Danlos Syndrome (EDS) hides in plain sight, leaving countless patients struggling with chronic pain and dislocations while searching for answers. In this captivating episode, Dr. Dean Mitchell interviews Dr. Bernadette Riley, a leading expert in EDS, to shine a light on this complex and often misunderstood condition. Learn about its mysterious link to mast cell activation, the challenges of hypermobility, and the innovative treatments transforming lives. Discover how Dr. Riley's pioneering approach at the NYIT EDS Hypermobility Center blends personalized care with hope for future breakthroughs, including biomarkers and specialized therapies. This is more than a podcast—it’s a li...

Why does your stomach hurt after meals? Could it be something serious, or is it just stress? In this enlightening episode of The Smartest Doctor in the Room, Dr. Dean Mitchell sits down with Dr. Doug Adler, a renowned gastroenterologist and expert in complex GI cases, to uncover the mysteries of chronic abdominal pain. They discuss common yet misdiagnosed conditions, cutting-edge diagnostic techniques, and why second opinions could save lives. Whether you're curious about pancreatic health, liver detox myths, or the latest advancements in GI treatments, this episode is packed with vital insights for anyone seeking answers about their...

Join us for an enlightening episode of "The Smartest Doctor in the Room" as we delve into the perplexing world of chronic sinusitis with our special guest, Dr. Aria Jafari, an assistant professor of Otolaryngology at the University of Washington School of Medicine. Chronic sinusitis is one of the most common chronic medical conditions, yet remains shrouded in mystery, often baffling even specialists.


In this episode, Dr. Jafari and host Dr. Dean Mitchell explore the nuanced differences between acute and chronic sinusitis, revealing how these conditions affect individuals' quality of life on multiple levels. More intriguingly...

Dive into the intense world of NYC's emergency response with veteran paramedic Anthony Almogero, author of Riding the Lightning. From life-or-death calls and grueling realities of COVID-19 to the overlooked struggles and resilience of EMS workers, Anthony shares raw stories that highlight both the courage and challenges faced by paramedics. Discover what truly happens behind the sirens and the sacrifices that keep our communities safe. An essential listen for anyone who wants an insider look into the frontline of emergency care and the unsung heroes who provide it.

In this episode of The Smartest Doctor in the Room, host Dr. Dean Mitchell explores the world of Multiple Sclerosis (MS) with the renowned Dr. Saoud Sadiq, director of the Tisch Multiple Sclerosis Research Center in Manhattan. MS is a diagnosis that can strike fear, particularly in young women in their 20s and 30s. Together, Dr. Mitchell and Dr. Sadiq delve into the evolution of MS treatments, from the limited options of the past to the groundbreaking therapies available today.

Dr. Sadiq shares his inspiring journey from Kenya to becoming a leader in MS research and unpacks...

In this special episode of The Smartest Doctor in the Room, we welcome back Dr. Dana Cohen, a leading functional medicine expert and our very first guest from five years ago. Dr. Cohen discusses her new book, Fuel Up, co-authored with Colin Sapphire, founder of Nutribullet. Together, they explore the transformative power of smoothies in reducing ultra-processed foods and boosting nutrition in a simple, enjoyable way. From practical smoothie recipes to insights on hydration and essential nutrients, this conversation dives into sustainable approaches for health without restrictive diets. Tune in to learn how Fuel Up can help make nutritious...

In this episode of The Smartest Doctor in the Room, Dr. Dean Mitchell is joined by Dr. Theoharis Theoharides, a leading expert on Mast Cell Activation Syndrome (MCAS). They uncover the hidden power of mast cells—cells once thought to only trigger allergies but now linked to long COVID, chronic fatigue, neurological symptoms, and more. From surprising triggers like stress and foods to the latest treatment options, they dive deep into the fascinating science and practical solutions for those dealing with complex, chronic symptoms. This conversation is a must-listen for anyone seeking answers to elusive health challenges.

Join us for an eye-opening conversation on "The Smartest Doctor in the Room" podcast as we welcome Dr. Jeffrey Kuhlman, a former White House physician who served three U.S. presidents: Clinton, Bush, and Obama. Dr. Kuhlman shares insights from his new book, Transforming Presidential Healthcare, and reflects on the high-stakes world of providing medical care to the nation’s top leaders. Listen as we delve into the unique dynamics of treating VIPs, the complexities of decision-making under pressure, and Dr. Kuhlman’s take on the need for mental and physical fitness criteria for presidential candidates. From intense trauma trai...

In this insightful episode of "The Smartest Doctor in the Room," we explore the complex world of PTSD (Post-Traumatic Stress Disorder) and trauma recovery with expert Dr. Dave Rabin. We dive deep into the latest treatments for PTSD, including groundbreaking therapies involving psychedelics like MDMA and ketamine. Dr. Rabin sheds light on how trauma rewires the brain, the role of heart rate variability as a recovery marker, and the profound impact of language on healing. Tune in to learn how modern psychiatry is evolving and offering new hope to veterans, trauma survivors, and many others.

In this episode of The Smartest Doctor in the Room, host Dr. Dean Mitchell delves into the transformative world of allergy treatment with guest Dr. Hugh Windom, a pioneering allergist with over five decades of experience. Together, they explore the evolution of allergy treatments, from outdated methods to cutting-edge therapies like oral immunotherapy (OIT) and sublingual immunotherapy (SLIT). Tune in to hear their thoughts on the latest advances in food allergy treatments, the role of biologics like Xolair, and the future of allergy care. Whether you're a healthcare professional or someone affected by allergies, this conversation offers valuable insights...

Dr. Dean Mitchell sits down with Dr. John DeWitt, one of the leading minds in sports science and biomechanics, for an in-depth look at how cutting-edge technology is changing the game for professional athletes. As the Director of Applied Sports Science at Rice Athletics and a former senior biomechanic at NASA, Dr. DeWitt has worked with some of the best in the business, from the Houston Rockets to the Chicago Cubs. His insights into biomechanics and data-driven performance enhancement are revolutionizing how athletes train, perform, and avoid injuries.

In this episode of The Smartest Doctor in the...

In this insightful episode, we explore the intersection of spirituality and healthcare with Dr. Robert Klitzman, a professor of psychiatry and bioethics expert from Columbia University. Together, we delve into the role of prayer, chaplaincy, and spirituality in modern medicine, asking tough questions: Can prayer truly aid recovery? How has the shift from religious-based hospitals to science-driven institutions impacted patient care? Dr. Klitzman shares personal stories, his journey through grief, and his thoughts on how faith, hope, and human connection play critical roles in healing. Whether you're spiritual, religious, or simply curious, this episode offers a thought-provoking look at how...

In this episode of "The Smartest Doctor in the Room," we dive deep into a critical but often overlooked topic: should future presidential candidates be required to undergo medical health fitness assessments? With less than two months until the next presidential election, we explore why it's more important than ever for our leaders to be physically and mentally fit. Drawing from real-world examples, historical insights, and expert medical knowledge, we discuss essential health markers such as cardiovascular health, lung capacity, mental stamina, and even empathy. Is it time to implement mandatory fitness tests for the presidency? Tune in for an...

In this episode of "The Smartest Doctor in the Room" podcast, we dive into the fascinating world of kidney health with Dr. David Goldfarb, a renowned nephrologist and kidney stone specialist from NYU Grossman School of Medicine. Discover why the kidneys are much more than just a waste-filtering organ and how they play a vital role in maintaining the body's chemistry and overall health. Dr. Goldfarb shares insights on hydration, the real impact of popular sports drinks, the latest on kidney disease prevention, and his personal journey that led him to specialize in kidney stones. Tune in to learn practical...

In this fascinating episode, we dive deep into the world of neurosurgery with Dr. Theodore Schwartz, a leading neurosurgeon at Weill Cornell Medicine and author of Gray Matters. Ever wondered what it’s like to operate on the human brain? Dr. Schwartz walks us through the pressures, intricacies, and emotional toll of being a brain surgeon. From his daily pre-surgery routine to moments of high-stakes decision-making in the OR, this episode offers a gripping insight into the realities of brain surgery. Dr. Schwartz also shares stories from his book, exploring the evolution of neurosurgery, the importance of sustained focus, and th...

In this insightful episode, Dr. Steven Quay, a physician-scientist whose groundbreaking research spans multiple fields, from pioneering methods in breast cancer diagnostics to delving into the origins of the COVID-19 pandemic. Dr. Quay shares his unconventional approaches to tackling some of the most pressing health challenges of our time, including his innovative ideas for early detection of breast cancer that challenge the traditional "cut, burn, and poison" model of treatment. And is controversial stance on the COVID-19 lab leak theory, examining the evidence he's gathered and his rationale for questioning the mainstream narrative. Discover how he challenges the norms of...

The FDA approved this month the Neffy nasal spray for treatment of anaphylaxis. Dr. Mitchell goes in depth comparing the safety and efficacy of Neffy vs. the Epipen. Listen carefully at the end where he gives his carefully constructed opinion.

Dr. Amiram Katz, is a well-respected neurologist in Connecticut.
We discuss a range of neurological conditions from migraines to seizures to Parkinson's. We also touch on some unconventional treatments like cannabis and immune globulin.

Dr. Dean Mitchell discusses how artificial intelligence in medicine can benefit everyone in this episode with Dr. Michael Segal, pediatric neurologist and founder of SimulConsult. They explore how AI aids doctors in making faster, more accurate diagnoses, leading to better patient care. Dr. Segal explains how SimulConsult’s AI software simplifies complex medical data, ensuring patients receive the most informed treatment. Unlike general search engines or tools like ChatGPT, this software is designed to support healthcare professionals directly. The episode also includes a live demo, showing how AI can help doctors quickly pinpoint the right diagnosis, improving healthcare outcomes for al...

Dr. Richard Doty, the director of the University of Pennsylvania's Perelman School of Medicine Smell and Taste Center, discusses the connection between these senses and neurologic and autoimmune diseases. We also discuss the truth behind your body scent and attractiveness.

An ER can be a scary place, so when should you go if you are sick? Dr. Tony Dajer, an experienced ER physician discusses when you should go to an ER and how to get the best treatment. We discuss how even celebrities don't always get the best care, but why you can.

Medical news can be exciting or controversial. However, the key to any research is its validity through statistical analysis. Professor Chris Schmid, is the Head of Biostatistics at Brown University, and shares his wealth of knowledge how to interpret medical studies.

POTS is a condition where the heart races uncontrollably for no reason. Since COVID the number of POTS cases has risen dramatically. It also has affected patients with Diabetes, Chronic fatigue Syndrome and Ehrlos-Danlos Syndrome. Dr. William Cheshire, is a national neurology expert from the Mayo Clinic on diseases of the Autonomic Nervous System and how it affects POTS.

Dr. Debra Muth, is a well-known naturopathic doctor in Wisconsin, and we discuss the differences in being treated by a naturopathic doctor vs. a medical doctor. We discuss treating Candida with herbs and botanicals.

Dr. Bob Arnot, a best-selling author, journalist, humanitarian has had a wild ride as a physician, who has taken his work all over the world. Listen to this fascinating conversation of his adventures.

Dr. Joseph Cappella, is a professor at University of Pennsylvania, who wrote a recent article on how to improve the patient-doctor visit. We discuss how doctors can be better at communicating to their patients, and how patients can be better prepared for their visit.

Dr. Neil Nathan, a leading functional medicine practitioner and author, has just released his new book: The Sensitive Patient's Healing Guide. He covers why some patients are highly sensitive to foods, supplements, medications and the environment - like EMFs.

Brenda Janotha is an Associate Dean at the Stonybrook University Medical Center. We discuss how nurses' roles have changed and their role in today's current healthcare system.

Lisa Ripi is an acupuncturist for the NFL players and her patients. She discusses how acupuncture works and who can be helped by this treatment.

Dr. Paul Offit in his new book, Tell Me When It's Over, discusses everything you need to know going forward regarding COVID vaccines, boosters and medications.

Drs. Maayan Levy and Benjamin Abramoff, are leading researchers on Long COVID at the Perelman School of Medicine. There recent paper on the new findings in Long COVID shed light on what's gone wrong- and offer hope for new treatments.

Dr. Craig Smith, Chairman in the department of Surgery at Columbia University Medical Center at NY- Presbyterian Hospital, has written a new book, Nobility in Small Things, about his life as a cardiothoracic surgeon; he also talks about his experience operating on former President Clinton.

Dr. Geral Lemole, a renowned cardiothoracic surgeon and integrative physician, discusses his book. Lymph and Longevity, and why we all need to take care of our lymphatic system.

Dr. Dave Rabin, a MD, PhD, founder of the product Apolloneuro discusses how this wearable device can relieve anxiety, stress and improve your sleep.

Dr. Tobias Carling, a top adrenal surgeon discusses how to diagnose and treat an adrenal tumor.

Dr. Nathan Wood, an instructor of medicine at Yale/New Haven Hospital and a chef shares the power of Culinary Medicine in staying Healthy.

Ozempic and Mounjaro are the latest weight loss drugs getting the attention. My guest, Dr. Philip Rabito, is a top endocrinologist in Manhattan and he discussed how he achieves long lasting weight loss in his patients.

Dr. Kyle Lapidus is a leading psychiatrist and researcher and we explore new treatments for depression such as ketamine and cranial stimulation.

Dr. Christopher Warren is an Assistant Professor of Preventive Medicine at Northwestern Medical School, and we discuss his epidemiology studies on why food allergies have been on the rise.

Dr. Allen Kaplan has been the premier allergy expert in the country on Chronic Urticaria. We discuss his views on Histamine Intolerance, Mast Cell Activation - and even Alzheimer's disease.

Shemane Nugent has a new book out, Killer House, where she shares her difficult journey battling illness due to toxic mold.

Dr. Mikkael Sekeres, is the chief of hematology at the University of Miami's Sylvester Comprehensive Cancer Center. We discuss his book " When Blood Breaks Down-Life Lessons from Leukemia."  He gives great insight on what should you do if diagnosed with a blood cancer.

Dr. Dean Mitchell reviews a recent paper in the medical literature showing new findings in Long COVID patients that also applies to other chronic viral syndromes that cause chronic fatigue and brain fog.

Dr. Tom Chiller, is the head of the CDC branch of mycotic diseases. We discuss the whole range of fungal diseases, including yeasts like Candida. Find out why it's important to be aware of this area of infections.

Dr. Abhinav Singh, is the sleep consultant to the Indiana Pacers basketball team. His book, Sleep to Heal has a ton of tips to help anyone sleep better. 

Dr. Donald Redelmeier, a Professor at the University of Toronto Medical School, is an expert in training doctors how to reduce medical errors. He shares how he thinks doctors should think.

Dr. Anupam Jena and Dr. Christopher Worsham teach at Harvard Medical School and their new book, Random Acts of Medicine reveals the hidden forces that impact patient care.

Dr. Peter Muran, the founder of the IV Vitamin Institute discusses the benefits of IV vitamin therapy and the uses in conditions ranging from Addiction to Alzheimer's disease.

Bioelectronic medicine is not widely known to the public. The handheld Gammacore device can be used to treat migraines and a variety of other illnesses. Dr. Peter Staats, a leader in this field tells us why.

Dr. Marjorie Crandall is a PhD mycology researcher and Candida consultant, who has just published the best book on Candida I've ever read: Overcoming Yeast Infections. We discuss the proper way to diagnose, treat, and the dietary truths and myths.

Dr. Michael Segal is the founder of Simulconsult, a company that provides software that helps clinicians make difficult diagnoses. We also discuss the pro and cons of AI in medicine.

Dr. Nezar Al-hebshi, is an associate Professor at the Kornberg School of Dentistry and the co-director of the Oral Microbiome Research Center at Temple University in Philadelphia. We discuss why the mouth is an important immune organ and how to keep it strong and healthy.

Dr. Avindra Nath is a Senior Scientist and leading expert at the NIH on post-viral neurological syndromes. We discuss what is brain fog from COVID and other viruses and potential treatments.

Dr. Michael Segal, is a well-recognized pediatric neurologist, who discusses the hidden benefits of children and adults with ADD

Dr. Alexandra Santos, a leading expert from the UK on using the Basophil Activation Test(BAT) to diagnose and follow food allergy patient's progress on treatment.

Dr. Helen Ouyang is a ER physician at New York Presbyterean Weil-Cornell Hospital and in between her hectic ER shifts writes long articles for The New York Times Magazine. We discuss a few of the articles and her view of life in the ER.